The Role of HVAC in Maintaining Cleanroom Standards

Maintaining stringentness is vital in pharmaceutical, manufacturing, biotechnology, and semiconductor production environments, where precision and cleanliness are paramount to ensuring efficient and safe practices. Heating, ventilation, and air conditioning (HVAC) systems are central to your efforts to create and maintain a functional cleanroom.

Let’s explore how HVAC promotes adherence to cleanroom standards and preserves the integrity of high-stakes projects.

What Are Cleanroom Standards?

Cleanroom standards are maximum particle allowances established by entities like the International Standards Organization (ISO). Cleanrooms are classified according to the size and number of particles allowed per volume of air. According to this classification system, a cleanroom with fewer particles will have a lower ISO class.

For example, ISO class 9 is standard room air. Rooms in this class can have 35,200,000 or more 0.5um (half a micron) particles in a cubic meter of air. ISO class 1 is the “cleanest” cleanroom. Spaces in this category can have no more than 10 particles per cubic meter of air. The particles are measured in increments of one-tenth of a micron.

How HVAC Systems Maintain Cleanroom Standards

Your HVAC equipment helps maintain cleanroom standards by providing the following:

Temperature Control

Maintaining a stable temperature is crucial in cleanrooms to ensure the consistency and quality of sensitive operations. HVAC systems are designed to provide precise temperature control and prevent fluctuations that could affect processes or degrade materials. Advanced units can maintain temperature within narrow tolerances.

Humidity Control

Humidity control represents a critical component of cleanroom standards. Excessive moisture can promote microbial growth. If you are engaging in activities like chip manufacturing, even minor humidity variations can damage sensitive equipment.

HVAC systems equipped with dehumidifiers and humidifiers help maintain ideal moisture levels in the air. Your specific humidity targets will vary depending on the project you are undertaking. However, many systems aim for a humidity threshold between 30% and 50%.

Airflow Management

Airflow management represents a cornerstone of cleanroom design. HVAC systems ensure a consistent and unidirectional flow of air. Top-end solutions use laminar flow hoods and high-efficiency particulate air (HEPA) filters to remove contaminants. In addition, the airflow pattern is designed to sweep particles away from critical areas and toward exhaust vents.

Must-Have HVAC Components

Cleanroom HVAC solutions need all of the typical parts, such as ductwork and a compressor. They also require other components, such as:

Air Filtration

HEPA and ultra-low penetration air (ULPA) filters remove particles as small as 0.3 microns with an efficiency of 99.99% or higher. These filters are installed in various stages of the HVAC system to ensure that incoming air is thoroughly cleaned before entering your workspace.

Use filters recommended by your manufacturer or system designer. For specific questions about air filtration, contact The Severn Group. Our team assists clients in maintaining cleanroom standards via our consultative, maintenance, and system design solutions. We also ensure adequate filtration to keep contaminants out of your cleanroom.

Pressurization

Pressurization controls the flow of air between different areas of the cleanroom, preventing contaminants from ingressing. The HVAC system maintains positive pressure in cleaner areas, pushing air out and preventing contaminants from entering the workspace. Conversely, negative pressure can be used in containment areas to ensure that hazardous particles do not escape into the environment.

Ventilation

Cleanroom ventilation systems are designed to provide many air changes per hour (ACH). Depending on the class of your cleanroom, HVAC solutions will typically facilitate dozens, if not hundreds, of ACH. The frequent exchanges of air help remove airborne particles and maintain the desired level of cleanliness.

The ventilation equipment also introduces fresh air and removes stale air, ensuring the environment remains healthy and contaminant-free.

Cleanroom HVAC Systems in Action

Numerous industries depend on HVAC systems to create and maintain cleanroom environments. A few examples include:

Pharmaceutical Manufacturing

Maintaining a contaminant-free environment in pharmaceutical manufacturing is critical to ensuring product safety and efficacy. Engineers design HVAC systems in these cleanrooms to provide precise temperature and humidity control. HEPA filters remove airborne particles and maintain positive pressure to prevent contamination. In addition, regular maintenance and validation are crucial to complying with stringent regulatory standards.

Semiconductor Production

Semiconductor cleanrooms require extremely low levels of particulate contamination to prevent microchip defects. HVAC systems in these environments use ULPA filters and advanced airflow management to achieve cleanroom standards. Air change rates are also higher to prevent particulates from penetrating the environment.

Biotech

Biotechnology laboratories often work with sensitive biological materials that require strict environmental controls. Therefore, HVAC systems in these cleanrooms use pressurization to prevent biologics from escaping into the environment. Regular calibration and validation ensure that environmental parameters meet the required standards for research and production.

How to Maintain Standards With Severn Group

A great HVAC system will promote cleanliness and exceptional air quality in your cleanroom. However, you must maintain your equipment regularly. Here are a few tips to ensure your space aligns with ISO cleanroom standards:

  • Regularly swap out filters
  • Inspect your system
  • Calibrate and validate your equipment
  • Outsource maintenance

That is why The Severn Group offers custom design and implementation services. We can assist with new construction projects or retrofit your existing facility with a robust HVAC system that maintains cleanroom standards. Contact our team to learn more.

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